40. Cryo-EM of amyloid fibrils: Advances, challenges, and translational applications
Dylan Valli and Michał Maj*. Current Approaches to Cryo-Electron Microscopy (in Progress in Molecular Biology and Translational Science Vol 223) , 2026. DOI:10.1016/bs.pmbts.2026.03.007
39. Exploring Excited State Proton Transfer Dynamics upon Ultraviolet Excitation
Nidhi Kaul, Alfy Benny, Vasilis Petropoulos, Michał Maj, Giulio Cerullo, Margherita Maiuri*, and Gregory D. Scholes*. J. Phys. Chem. A, 2026, 130, 12, 2566–2574. DOI:10.1021/acs.jpca.5c08622
38. A Highly Sensitive Water-Soluble Donor−Acceptor Dye for Early-Stage Amyloid Aggregation Kinetics
Giorgio Scattolini, Carlos Enrique Torres-Méndez, Dylan Valli, Mikołaj I. Kuska, Nidhi Kaul, Leif Hammarström, Haining Tian, and Michał Maj*. J. Phys. Chem. B, 2026, 130, 11, 3042–3053. DOI:10.1021/acs.jpcb.5c07705
37. Two-dimensional infrared spectroscopy of solute-solvent complexes from linear-scaling DFT and machine learning
Michał Maj, J. Chem. Phys., 2026, 164, 084106. DOI:10.1063/5.0303526
36. Two-dimensional FTIR methods on amyloid aggregation and folding pathways
Michał Maj*. Structural Studies of Amyloid-β (in Methods in Enzymology, Vol 729), 2026. DOI:10.1016/bs.mie.2026.01.027
35. Chemical mechanism of allosteric and asymmetric dark reversion in a bacterial phytochrome uncovered by cryo-EM
Szabolcs Bódizs, Anna-Lena M. Fischer, Miklós Cervenak, Sayan Prodhan, Michał Maj, and Sebastian Westenhoff. J. Am. Chem. Soc., 2025, 147, 49, 45701–45711. DOI:10.1021/jacs.5c17531
34. High-Resolution structure of proIAPP(1-48) fibrils suggests a mechanistic pathway for diabetes-associated IAPP fibril polymorphs
Dylan Valli and Michał Maj*. RSC Chem. Biol., 2025 DOI: 10.1039/D5CB00228A
33. Detection of a hybrid PrPfr state in the dark reversion of a bathy phytochrome indicates inter-dimer allostery
Sayan Prodhan, Petra Meszaros, Szabolcs Bodizs, Yalin Zhou, Michał Maj, and Sebastian Westenhoff. Phys. Chem. Chem. Phys., 2025, 27, 20279-20287. DOI:10.1039/D5CP01831E
32. Cryo-EM exposes diverse polymorphism in IAPP mutants to guide the rational design of peptide-based therapeutics
Saik Ann Ooi, Dylan Valli, Mikołaj I. Kuska, Helena Marí, Himanshu Chaudhary, Weixiao Yuan Wahlgren, Sebastian Westenhoff, Alesia A. Tietze, Anna Novials, Joan-Marc Servitja, and Michał Maj*. J. Mol. Biol., 2025, 437, 21, 169405. DOI: 10.1016/j.jmb.2025.169405
31. Observation of early events in the photoactivation of Myxobacterial phytochrome using time-resolved serial femtosecond crystallography
Tek Narsingh Malla, Luis Aldama, Viridiana Leon, Denisse Feliz, Hao Hu, Isaiah Thomas, Andrea Cellini, Weixiao Y. Wahlgren, Amke Nimmrich, Sabine Botha, Ray Sierra, Mark S. Hunter, Frédéric Poitevin, Stella Lisova, Alexander Batyuk, Gregory Gate, Rebecca Jernigan, Christopher J. Kupitz, Pjotr Maj, Petra Meszaros, Moona Kurttila, Leonardo Monrroy, Fangjia Luo, Shigeki Owada, Jungmin Kang, Chavdar Slavov, Michał Maj, Candice Gautier, Maithri Kashipathy, Alexandra Tolstikova, Valerio Mariani, Anton Barty, Frank Moss, Peter Schwander, Haiguang Liu, Sébastien Boutet, Petra Fromme, Heiki Takala, Janne A. Ihalainen, Uwe Weierstall, Sebastian Westenhoff, Emina A. Stojković and Marius Schmidt. Commun. Chem., 2025, 8, 183. DOI: 10.1038/s42004-025-01578-z
30. Cryo-electron Microscopy Provides Mechanistic Insights into Solution-dependent Polymorphism and Cross-aggregation Phenomena of the Human and Rat Islet Amyloid Polypeptides
Dylan Valli, Saik Ann Ooi, Ibrahim Kaya, Asger Berg Thomassen, Himanshu Chaudhary, Tobias Weidner, Per E. Andrén and Michał Maj*. Biochemistry, 2025, 64, 12, 2583–2595. DOI: 10.1021/acs.biochem.5c00042/
29. Solvatochromic charge model of isonitrile probes for investigating hydrogen-bond dynamics with 2DIR spectroscopy
Michał Maj. J. Chem. Phys., 2025, 162, 014113. DOI: 10.1063/5.0242857
28. Improving cryo-EM grids for amyloid fibrils using interface-active solutions and spectator proteins
Dylan Valli, Saik Ann Ooi, Giorgio Scattolini, Himanshu Chaudhary, Alesia A. Tietze, and Michał Maj*. Biophys. J., 2024, 123, 6, 718-729. DOI: 10.1016/j.bpj.2024.02.009
27. Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography
Andrea Cellini, Madan Kumar Shankar, Amke Nimmrich, Leigh Anna Hunt, Leonardo Monrroy, Jennifer Mutisya, Antonia Furrer, Emma V. Beale, Melissa Carrillo, Tek Narsingh Malla, Piotr Maj, Lidija Vrhovac, Florian Dworkowski, Claudio Cirelli, Philip J. M. Johnson, Dmitry Ozerov, Emina A. Stojković, Leif Hammarström, Camila Bacellar, Jörg Standfuss, Michał Maj, Marius Schmidt, Tobias Weinert, Janne A. Ihalainen, Weixiao Yuan Wahlgren & Sebastian Westenhoff. Nat. Chem., 2024, 16, 624-632. DOI: 10.1038/s41557-023-01413-9
26. Protein Cohabitation: Long-term Immunoglobulin G Storage at Room Temperature
Pankaj Bharmoria, Saik Ann Ooi, Andrea Cellini, Daniel Tietze, Michał Maj, Kasper Moth-Poulsen, and Alesia A. Tietze. J. Mater. Chem. B., 2023, 11, 5400-5405. DOI: 10.1039/d3tb00161j
25. Ground-state heterogeneity and vibrational energy redistribution in bacterial phytochrome observed with femtosecond 2D IR spectroscopy
Manoop Chenchiliyan, Joachim Kübel, Saik Ann Ooi, Giacomo Salvadori, Benedetta Mennucci, Sebastian Westenhoff, and Michał Maj*. J. Chem. Phys., 2023, 158, 085103. DOI: 10.1063/5.0135268. Part of a special issue : “Celebrating 25 Years of Two-dimensional Infrared (2D IR) Spectroscopy”
24. Metastable intermediate during hIAPP aggregation catalyzed by membranes as detected with 2D IR spectroscopy
Sidney S. Dicke, Michał Maj, Caitlyn R. Fields, and Martin T. Zanni. RSC Chem. Biol., 2022, 3, 931-940. DOI: 10.1039/D2CB00028H
23. Giving Voice to the Weak: Application of Active Noise Reduction in Transient Infrared Spectroscopy
Joachim Kübel, Sebastian Westenhoff, and Michał Maj*.
Chem. Phys. Lett., 2021, 783, 139059. DOI: 10.1016/j.cplett.2021.139059
22. High-resolution crystal structures of transient intermediates in the phytochrome photocycle
Melissa Carrillo, Suraj Pandey, Juan Sanchez, Moraima Noda, Ishwor Poudyal, Luis Aldama, Tek Narsingh Malla, Elin Claesson, Weixiao Yuan Wahlgren, Denisse Feliz, Vukica Srajer, Michał Maj, Leticia Castillon, So Iwata, Eriko Nango, Rie Tanaka, Tomoyuki Tanaka, Luo Fangjia, Kensuke Tono, Shigeki Owada, Sebastian Westenhoff, Emina A. Stojkovic, and Marius Schmidt.
Structure, 2021, 29, 7, 743-754. DOI: 10.1016/j.str.2021.03.004
21. Ultrafast Structural Changes within a Photosynthetic Reaction Centre
Robert Dods, Petra Båth, Dmitry Morozov, Viktor Ahlberg Gagner, David Arnlund, Hoi Ling Luk, Joachim Kübel, Michał Maj, Adams Vallejos, Cecilia Wickstrand, Robert Bosman, Kenneth R. Beyerlein, Garrett Nelson, Mengning Liang, Despina Milathianaki, Joseph Robison, Rajiv Harimoorthy, Peter Berntsen, Erik Malmerberg, Linda Johansson, Rebecka Andersson, Sergio Carbajo, Elin Claesson, Chelsie E. Conrad, Peter Dahl, Greger Hammarin, Mark S. Hunter, Chufeng Li, Stella Lisova, Antoine Royant, Cecilia Safari, Amit Sharma, Garth J. WIlliams, Oleksandr Yefanov, Sebastian Westenhoff, Jan Davidsson, Daniel P. DePonte, Sebastien Boutet, Anton Barty, Gergely Katona, Gerrit Groenhof, Gisela Bränden, and Richard Neutze.
Nature, 2020, 589, 310–314. DOI: 10.1038/s41586-020-3000-7
20. The primary structural photoresponse of phytochrome proteins captured by a femtosecond X-ray laser
Elin Claesson, Weixiao Yuan Wahlgren, Heikki Takala, Suraj Pandey, Leticia Castillon, Valentyna Kuznetsova, Leocadie Henry, Melissa Carrillo, Matthijs Panman, Joachim Kübel, Rahul Nanekar, Linnéa Isaksson, Amke Nimmrich, Andrea Cellini, Dmitry Morozov, Michał Maj, Moona Kurttila, Robert Bosman, Eriko Nango, Rie Tanaka, Tomoyuki Tanaka, Luo Fangjia, So Iwata, Shigeki Owada,Keith Moffat, Gerrit Groenhof, Emina A. Stojkovic, Janne A. Ihalainen, Marius Schmidt and Sebastian Westenhoff. eLife, 2020, 9:e53514. DOI: 10.7554/eLife.53514
19. Transient IR Spectroscopy Identifies Key Interactions and Unravels New Intermediates in the Photocycle of a Bacterial Phytochrome
Joachim Kübel, Manoop Chenchilyan, Saik Ann Ooi, Emil Gustavsson, Linnéa Isaksson, Valentyna Kuznetsova, Janne A. Ihalainen, Sebastian Westenhoff and Michał Maj*.
Phys. Chem. Chem. Phys., 2020, 22, 9195-9203. DOI: 10.1039/C9CP06995J FRONT COVER ARTICLE
18. Ultrafast Chemical Exchange Dynamics of Hydrogen Bonds Observed via Isonitrile Infrared Sensors: Implications for Biomolecular Studies
Joachim Kübel, Giseong Lee, Saik Ann Ooi, Sebastian Westenhoff, Hogyu Han, Minhaeng Cho and Michał Maj*.
J. Phys. Chem. Lett., 2019, 10, 24, 7878-7883. DOI: 10.1021/acs.jpclett.9b03144
Pre-Uppsala
Lauren E. Buchanan, Michał Maj, Emily B. Dunkelberger, Pin-Nan Cheng, James S. Nowick and Martin T. Zanni, Biochemistry (2019), 57 (46), 6470-6478
Megan K. Petti, Justin P. Lomont, Michał Maj and Martin T. Zanni, J. Phys. Chem. B. (2018), 122 (6), 1771-1780
15. Spectroscopic signature for stable β-amyloid fibrils versus β-sheet-rich oligomers
Justin P. Lomont, Kacie L. Rich, Michał Maj, Jia-Jung Ho, Joshua S. Ostrander and Martin T. Zanni, J. Phys. Chem. B. (2018), 122 (1), 144-153
Michał Maj, Justin P. Lomont, Kacie L. Rich, Ariel M. Alperstein and Martin T. Zanni, Chem. Sci. (2018), 9 (2), 463-474
Huong T. Kratochvil, Michał Maj, Kimberly Matulef, Alvin W. Annen, Jared Ostmeyer, Eduardo Perozo, Benoît Roux, Francis I. Valiyaveetil and Martin T. Zanni, J. Am. Chem. Soc. (2017), 139 (26), 8837-8845
Michał Maj, Changwoo Ahn, Bartosz Błasiak, Kyungwon Kwak, Hogyu Han and Minhaeng Cho, J. Phys. Chem. B. (2016), 120 (50), 13001-13001
11. Isonitrile as an ultrasensitive infrared reporter of hydrogen-bonding structure and dynamics
Michał Maj, Changwoo Ahn, Bartosz Błasiak, Kyungwon Kwak, Hogyu Han and Minhaeng Cho, J. Phys. Chem. B. (2016), 120 (39), 10167-10180
Huong T. Kratochvil, Joshua K. Carr, Kimberly Matulef, Alvin W. Annen, Hui Li, Michał Maj, Jared Ostmeyer, Arnaldo L. Serrano, H Raghuraman, Sean D. Moran, JL Skinner, Eduardo Perozo, Benoît Roux, Francis I. Valiyaveetil and Martin T. Zanni, Science (2016), 353 (6303), 1040-1044
9. Site-specific characterization of cytochrome P450cam conformations by infrared spectroscopy
Edward J. Basom, Michał Maj, Minhaeng Cho, Megan C. Thielges, Anal. Chem. (2016), 88 (12), 6598-6606
Michał Maj, Kyungwon Kwak and Minhaeng Cho, ChemPhysChem (2015), 16 (16), 3468-3476
7. Modulation of the hydrogen bonding structure of water by renal osmolytes
Pramod Kumar Verma, Hochan Lee, Joon-Young Park, Joon-Hyung Lim, Michał Maj, Jun-Ho Choi, Kyung-Won Kwak and Minhaeng Cho, J. Phys. Chem. Lett. (2015), 6 (14), 2773-2779
6. Distributed multipolar expansion approach to calculation of excitation energy transfer couplings
Bartosz Błasiak, Michał Maj, Minhaeng Cho and Robert W Góra, J. Chem. Theory Comput. (2015), 11 (7), 3259-3266
Michał Maj, Changwoo Ahn, Dorota Kossowska, Kwanghee Park, Kyungwon Kwak, Hogyu Han and Minhaeng Cho, Phys. Chem. Chem. Phys. (2015), 17 (17), 11770-11778
4. Infrared Pump–Probe Study of Nanoconfined Water Structure in Reverse Micelle
Jooyong Lee, Michał Maj, Kyungwon Kwak, Minhaeng Cho, J. Phys. Chem. Lett. (2014), 5 (19), 3404-3407
3. Vibrational dynamics of thiocyanate and selenocyanate bound to horse heart myoglobin
Michał Maj, Younjun Oh, Kwanghee Park, Jooyong Lee, Kyung-Won Kwak, Minhaeng Cho, J. Chem. Phys. (2014), 140 (23), 06B618_1
Michał Maj, Jonggu Jeon, Robert W Góra and Minhaeng Cho, J. Phys. Chem. A. (2013), 117 (29), 5909-5918
1. Resonance-assisted hydrogen bonds revisited. Resonance stabilization vs. charge delocalization
Robert W Góra, Michał Maj and Sławomir J Grabowski, Phys. Chem. Chem. Phys. (2013), 15 (7), 2514-2522